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2015

Olefinic C-H functionalization through radical alkenylation
Shan Tang, Kun Liu, Chao Liu, and Aiwen Lei*
Chem. Soc. Rev. 2015, 44(5), 1070-1082.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CS/C4CS00347K#!divAbstract


External Oxidant-Free Oxidative Cross-Coupling: A Photoredox Cobalt-Catalyzed Aromatic C-H Thiolation for Constructing C-S Bonds
Guoting Zhang, Chao Liu, Hong Yi, Qingyuan Meng, Changliang Bian, Hong Chen, Jing-Xin Jian, Li-Zhu Wu*, and Aiwen Lei*
J. Am. Chem. Soc. 2015, 137, 9273–9280.

Link:http://pubs.acs.org/doi/10.1021/jacs.5b05665


Revealing the halide effect on the aerobic oxidation kinetics of Cu(I) to Cu(II)
Deng, Y.; Zhang, G. H.; Qi, X. T.; Liu, C.; Miller, T. Jeffrey; Kropf, A. Jeremy; Bunel, E. Emilio; Lan, Y.; Lei, A. W.
Chem. Commun. 2015, 51, 318-321.

Link:http://pubs.rsc.org/en/Results?ArtRefJournalName=Chemical%20Communications&ArtRefStartPage=318&ArtRefVolumeYear=51&fcategory=Journal
 

Evidence for the Interaction Between tBuOK and 1,10-Phenanthroline to form the 1,10-Phenanthroline Radical Anion: A Key Step for the Activation of Aryl Bromides by Electron Transfer
Yi, H.; Jutand, A.; Lei, A. W.
Chem. Commun. 2015, 51, 545 - 548.

Link:http://pubs.rsc.org/en/Results?ArtRefJournalName=Chemical%20Communications&ArtRefStartPage=545&ArtRefVolumeYear=51&fcategory=Journal

 
Bimetallic Zinc Complex --- Active Species in Coupling of Terminal Alkynes with Aldehydes via Nucleophilic Addition/Oppenauer Oxidation
Yuan, J. W.; Wang, J.; Zhang G. H.; Liu, C.; Qi, X. T.; Lan, Y.; Miller, T. Jeffrey; Kropf, A. Jeremy; Bunel, E. Emilio; Lei, A. W.
Chem. Commun. 2015, 51, 576 - 579.

Link:http://pubs.rsc.org/en/Results?ArtRefJournalName=Chemical%20Communications&ArtRefStartPage=576&ArtRefVolumeYear=51&fcategory=Journal
 

Aerobic C-N Bond Activation: A Simple Strategy to Construct Pyridines and Quinolines
Wu, K.; Huang, Z. L.; Liu, C.; Zhang, H.; Lei, A. W.
Chem. Commun. 2015, 51, 2286 - 2289.

Link:http://pubs.rsc.org/en/Results?ArtRefJournalName=Chemical%20Communications&ArtRefStartPage=2286&ArtRefVolumeYear=51&fcategory=Journal
 

Copper-Catalysed Oxidative Alkenylation of Thioethers via Csp3-H Functionalization
Cao, H.; Liu, D.; Liu, C.; Hu, X. Q.; Lei, A. W.
Org. Biomol. Chem. 2015, 13, 2264 - 2266.

Link:http://pubs.rsc.org/en/Results?ArtRefJournalName=OB&ArtRefStartPage=2264&ArtRefVolumeYear=13&fcategory=Journal
 
  
Construction of N-Containing Heterocycles via Oxidative Intramolecular N-H/X-H Coupling
Jiwen Yuan, Chao Liu and Aiwen Lei*
Chem. Commun. 2015, 51, 1394 – 1409.

Link:http://pubs.rsc.org/en/results?artrefjournalname=chem.%20commun.&artrefstartpage=1394&artrefvolumeyear=2015&fcategory=journal
 
 
Silver-Mediated Selective Oxidative Cross-Coupling between C−H/P−H: A Strategy to Construct Alkynyl(diaryl)phosphine Oxide
Tao Wang, Songtao Chen, Ailong Shao, Meng Gao*, Yangfei Huang, and Aiwen Lei*
Org. Lett. 2015, 17, 118−121.

Link:http://pubs.acs.org/doi/10.1021/ol503341t

 
(E)-α, β-Unsaturated Amides from Tertiary Amines, Olefins and CO via Pd/Cu-Catalyzed Aerobic Oxidative N-Dealkylation
Renyi Shi, Hua Zhang, Lijun Lu, Pei Gan, Yuchen Sha, Heng Zhang, Qiang Liu, Matthias Beller* and Aiwen Lei*
Chem. Commun. 2015, 51, 3247 - 3250.

Link:http://pubs.rsc.org/en/content/articlelanding/2015/cc/c4cc08925a#!divAbstract

 
Iodine-Catalyzed Oxidative Coupling Reactions Utilizing C-H and X-H as Nucleophiles
Dong Liu, Aiwen Lei*
Chem. Asian. J., 2015, 10, 806 – 823.

Link:http://onlinelibrary.wiley.com/doi/10.1002/asia.201403248/abstract;jsessionid=B18006018159D604597597E5124A81E8.f02t04

 
Nickel-Catalyzed Selective Oxidative Radical Cross-Coupling: An Effective Strategy for Inert Csp3−H Functionalization
Dong Liu, Yuxiu Li, Xiaotian Qi, Chao Liu, Yu Lan*, and Aiwen Lei*
Org. Lett. 2015, 17, 998–1001.

Link:http://pubs.acs.org/doi/10.1021/acs.orglett.5b00104

 
O2-mediated C(sp2)–X bond oxygenation: autoxidative carbon–heteroatom bond formation using activated alkenes as a linkage.
Qingquan Lu, Jiyong Chen, Chao Liu, Zhiyuan Huang, Pan Peng, Huamin Wang and Aiwen Lei*
RSC Adv., 2015, 5, 24494–24498.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C4RA17106C#!divAbstract

 
Palladium/Copper-Catalyzed Aerobic Oxidative C–H Carbonylation for the Synthesis of o-Aminobenzoates
Wu Li, Zhengli Duan, Ru Jiang, and Aiwen Lei*
Org. Lett., 2015, 17(6), 1397-1400.

Link:http://pubs.acs.org/doi/10.1021/acs.orglett.5b00206

 
Copper-Catalyzed Radical/Radical C(sp3)-H/P-H Cross-Coupling: α-Phosphorylation of Aryl Ketone O-Acetyloximes
Jie Ke, Yuliang Tang, Hong Yi, Yali Li, Yongde Cheng, Chao Liu, and Aiwen Lei*
Angew. Chem. Int. Ed., 2015, 54, 6604-6607.

Link:http://onlinelibrary.wiley.com/doi/10.1002/anie.201501287/abstract
 

An Efficient [3+2] Cycloaddition for the Synthesis of Substituted Pyrazolo[1,5-c] Quinazolines
Tao Wang, Ailong Shao, Haiyan Feng, Shuwu Yang, Meng Gao, Jun Tian, Aiwen Lei*
Tetrahedron 2015, 71, 4473-4477.

Link:http://www.sciencedirect.com/science/article/pii/S0040402015003178?via%3Dihub

 
Oxidative Cross S-H/S-H Coupling: Selective Synthesis of Unsymmetrical Aryl tert-Alkyl Disulfanes
Jiwen Yuan, Chao Liu and Aiwen Lei*
Org. Chem. Front. 2015, 2, 677 - 680.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/QO/C5QO00027K#!divAbstract
 

A facile access for the C-​N bond formation by transition metal-​free oxidative coupling of benzylic C-​H bonds and amides
Jie Liu, Heng Zhang, Hong Yi, Chao Liu, and Aiwen Lei*
Sci. China Chem. 2015, 58, 1323-1328.

Link:https://link.springer.com/article/10.1007%2Fs11426-015-5381-2

 
Advances in Visible-light-mediated Oxidative Coupling Reactions
Guoting Zhang, Changliang Bian, Aiwen Lei*
Chin. J. Catal. 2015, 36, 1428–1439.

Link:http://www.sciencedirect.com/science/article/pii/S1872206715608853?via%3Dihub

 
Palladium-catalysed oxidative cross-esterification between two alcohols
Jianhui Xia, Ailong Shao, Shan Tang, Xinlong Gao, Meng Gao* and Aiwen Lei*
Org. Biomol. Chem., 2015, 13, 6154-6157.

Link:http://pubs.rsc.org/en/content/articlelanding/2015/ob/c5ob00677e#!divAbstract
 

Tuning radical reactivity by iodine in oxidative C(sp3)​-​H​/C(sp)​-​H cross-​coupling: an easy way toward furans and indolizines
Shan Tang, Kun Liu, Yue Long, Xiaotian Qi, Yu Lan* and Aiwen Lei*
Chem. Commun. 2015, 51, 8769-8772.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC01825K#!divAbstract

 
Iron-​Catalyzed Oxidative C-​H​/C-​H Cross-​Coupling between Electron-​Rich Arenes and Alkenes
Yiyang Ma, Dongchao Zhang, Zhiyuan Yan, Mengfan Wang, Changliang Bian, Xinlong Gao, Emilio E. Bunel*, and Aiwen Lei*
Org. Lett. 2015, 17(9), 2174–2177.

Link:http://pubs.acs.org/doi/10.1021/acs.orglett.5b00775
 

Iodine-Catalyzed C-H/S-H Oxidative Coupling: from 1,3-Diketones and Thiophenols to β-Dicarbonyl Thioethers
Hao Cao, Jiwen Yuan, Chao Liu, Xinquan Hu* and Aiwen Lei*
RSC Adv. 2015, 5, 41493 - 41496.

Link:http://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra04906g#!divAbstract

 
Autoinductive Thiolation/Oxygenation of Alkenes at Room Temperature
Qingquan Lu, Huamin Wang, Pan Peng, Chao Liu, Zhiyuan Huang, Yi Lu and   Aiwen Lei*
Org. Chem. Front. 2015, 2, 908 - 912.

Link:http://pubs.rsc.org/en/content/articlelanding/2015/qo/c5qo00102a#!divAbstract

 
Iodine-Catalyzed Radical Oxidative Annulation for the Construction of Dihydrofurans and Indolizines
Shan Tang, Kun Liu, Yue Long, Xinlong Gao, Meng Gao, and Aiwen Lei*
Org. Lett. 2015, 17(10), 2404-2407.

Link:http://pubs.acs.org/doi/10.1021/acs.orglett.5b00912

 
Carbon-Centered Radical Addition to C=X Bonds for C-X Bond Formations
Dong Liu, Chao Liu, Aiwen Lei*
Chem. Asian J. 2015, 10, 2040 – 2054.

Link:http://onlinelibrary.wiley.com/doi/10.1002/asia.201500326/abstract

 
Operando X-ray Absorption, EPR Evidence for Single Electron Redox in Copper Catalysis
Qingquan Lu, Jian Zhang, Pan Peng, Guanghui Zhang, Zhiliang Huang, Hong Yi,  Jeffrey T. Miller and Aiwen Lei*
Chem. Sci. 2015, 6, 4851-4854.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/SC/C5SC00807G#!divAbstract

 
Recent advances in oxidative coupling reactions
Zhang Jian, Lu Qingquan, Liu Chao, and Lei Aiwen*
Chin. J. Org. Chem. 2015, 35(4), 743-759.
 

Single-​Site Palladium(II) Catalyst for Oxidative Heck Reaction: Catalytic Performance and Kinetic Investigations
Hui Duan, Menghuan Li, Guanghui Zhang, James R. Gallagher, Zhiliang Huang, Yu Sun, Zhong Luo, Hongzhong Chen, Jeffrey T. Miller, Ruqiang Zou, Aiwen Lei*, and Yanli Zhao*
ACS Catal., 2015, 5, 3752–3759.

Link:http://pubs.acs.org/doi/10.1021/acscatal.5b00569

 
Dinuclear versus Mononuclear Pathways in Zinc Mediated Nucleophilic Addition: A Combined Experimental and DFT Study

Xiaotian Qi, Yingzi Li, Guanghui Zhang, Yang Li, Aiwen Lei,* Chao Liu* and   Yu Lan*
Dalton Trans., 2015, 44, 11165-11171.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/DT/C5DT01366F#!divAbstract
 

Synthesis of oxazoles by silver catalysed oxidative decarboxylation-cyclization of α-oxocarboxylates and isocyanides
Yiyang Ma, Zhiyuan Yan, Changliang Bian, Ke Li, Xiaowen Zhang, Mengfan Wang, Xinlong Gao, Heng Zhang* and Aiwen Lei*
Chem. Commun. 2015, 51, 10524-10527.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC02253C#!divAbstract

 
Copper-/Cobalt-Catalyzed Highly Selective Radical Dioxygenation of Alkenes
Qingquan Lu, Zhiliang Liu, Yi Luo, Guanghui Zhang, Zhiyuan Huang, Huamin Wang, Chao Liu, Jeffrey T. Miller, and Aiwen Lei*
Org. Lett. 2015, 17 (14), 3402–3405.

Link:http://pubs.acs.org/doi/10.1021/acs.orglett.5b01223
 
 
Visible Light Mediated Efficient Oxidative Benzylic sp3 C−H to Ketone Derivatives under Mild Conditions using O2
Hong Yi, Changliang Bian, Xia Hu, Linbin Niu and Aiwen Lei*
Chem. Commun. 2015, 51, 14046 - 14049.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC06015J#!divAbstract

 
Oxidative cross-coupling: an alternative way for C–C bond formations
Zhiyuan Huang, Shan Tang , Aiwen Lei*
Sci. Bull. 2015, 60, 1391-1394.

Link:http://www.sciencedirect.com/science/article/pii/S209592731630336X?via%3Dihub
 

Pd(OAc)2/S=PPh3 Accelerated Activation of gem-Dichloroalkenes for the Construction of 3-Arylchromones
Jianming Liu,* Weiwei Song, Yuanyuan Yue, Ren Liu, Hong Yi, Kelei Zhuo and   Aiwen Lei*
Chem. Commun. 2015, 51, 17576 – 17579.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC06334E#!divAbstract

 
Copper-Catalyzed Aerobic Decarboxylation/Ketooxygenation of Electron-Deficient Alkenes
Qingquan Lu, Pan Peng, Yi Luo, Ying Zhao, Minxian Zhou, Aiwen Lei*
Chem. Eur. J. 2015, 21, 18580 - 18583.

Link:http://onlinelibrary.wiley.com/doi/10.1002/chem.201503716/abstract
 

Which one is faster? A kinetic investigation of Pd and Ni catalyzed Negishi-type oxidative coupling reactions
Jie Xin, Guanghui Zhang, Yi Deng, Heng Zhang* and Aiwen Lei*
Dalt. Trans. 2015, 44, 19777 - 19781.

Link:http://pubs.rsc.org/en/Content/ArticleLanding/2015/DT/C5DT03386A#!divAbstract

 
Zinc-Catalyzed Dehydrogenative Cross-Coupling of Terminal Alkynes with Aldehydes: A Simple Access to Ynones
Shan Tang, Li Zeng, Yichang Liu, Aiwen Lei*
Angew. Chem. Int. Ed. 2015, 54, 15850 –15853.

Link:http://onlinelibrary.wiley.com/doi/10.1002/anie.201509042/abstract
 

Oxidative Coupling between Two Hydrocarbons: An Update of Recent C-H Functionalizations
Chao Liu, Jiwen Yuan, Meng Gao, Shan Tang, Wu Li, Renyi Shi, and Aiwen Lei*
Chem. Rev.2015, 115 (22), 12138–12204.

Link:http://pubs.acs.org/doi/10.1021/cr500431s

 
Evidence of Cu(I)/Cu(II) Redox Process by XAFS and EPR Spectroscopy: Direct Synthesis of Dihydrofurans from β-Ketocarbonyl Derivatives and Olefins

Hong Yi, Zhixiong Liao, Guanghui Zhang, Guoting Zhang, Chao Fan, Xu Zhang, Emilio E. Bunel, Chih-Wen Pao, Jyh-Fu Lee*, Aiwen Lei*
Chem. Eur. J. 2015, 21, 18925 - 18929.
Link:http://onlinelibrary.wiley.com/doi/10.1002/chem.201503822/abstract

 
NMP and O2 as Radical Initiator: Trifluoromethylation of Alkenes to Tertiary β‑Trifluoromethyl Alcohols at Room Temperature
Chao Liu, Qingquan Lu, Zhiyuan Huang, Jian Zhang, Fan Liao, Pan Peng, and Aiwen Lei*
Org. Lett. 2015, 17, 6034−6037.

Link:http://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b03035?journalCode=orlef7&quickLinkVolume=17&quickLinkPage=6034&selectedTab=citation&volume=17

 
Copper-Catalyzed Aerobic Oxidative Coupling: From Ketone and Diamine to Pyrazine
Kun Wu, Zhiliang Huang, Xiaotian Qi, Yingzi Li, Guanghui Zhang, Chao Liu, Hong Yi, Lingkui Meng, Emilio E. Bunel, Jeffrey T. Miller, Chih-Wen Pao, Jyh-Fu Lee*, Yu Lan*, and Aiwen Lei*
Sci. Adv. 2015, Vol. 1, no. 9, e1500656. DOI: 10.1126/sciadv.1500656.

Link:http://advances.sciencemag.org/content/1/9/e1500656

 
Autoxidative Coupling and Its Applications to C-H Functionalization
Qingquan Lu, Hong Yi; Aiwen Lei*
Acta Chim. Sinica 2015, 73, 1245—1249.
 

Tuning the Reactivity of Radical through a Triplet Diradical Cu(II) Intermediate in Radical Oxidative Cross-Coupling
Liangliang Zhou, Hong Yi, Lei Zhu, Xiaotian Qi, Hanpeng Jiang, Chao Liu, Yuqi Feng, Yu Lan* & Aiwen Lei*
Sci. Rep. 2015, 5, 15934, doi: 10.1038/srep15934.

Link:http://www.nature.com/articles/srep15934