New Paper:Iron-Catalyzed Oxidative Radical Cross-Coupling / Cyclization between Phenol and Olefin

New Paper:Iron-Catalyzed Oxidative Radical  Cross-Coupling / Cyclization between Phenol and Olefin

Angew. Chem. Int. Ed. 2012 Accepted

DOI: 10.1002/anie.201210023

Selectively  free: A highly  efficient and selective Fe-catalyzed oxidative radical cross-coupling /  cyclization to prepare dihydrobenzofurans under mild conditions had been established by  directly utilizing phenols and olefins as “CLEAN” nucleophiles. The mechanistic  investigations revealed that the reaction proceeds through a radical pathway  and the high selectivity is due to the Lewis acid.