Monthly Archives: March 2016

Annual Barbecue Party at Wuhan Forest Park

On Mar. 28th, 2016, we had a annual barbecue party at Wuhan forest park. Everyone of Lei’s group enjoyed the activity and had a wonderful day. After that, we took a piture to memory this beautiful spring scenery.

烧烤

 

 

New Paper: Solvent-Enabled Radical Selectivities: Controlled Syntheses of Sulfoxides and Sulfides

New Paper:

Solvent-Enabled Radical Selectivities: Controlled Syntheses of Sulfoxides and Sulfides

Huamin Wang, Qingquan Lu, Chaohang Qian, Chao Liu, Wei Liu, Kai Chen, and Aiwen Lei

Abstract: Controlling selectivity is of central importance to radical chemistry. However, the highly reactive and unstable radical intermediates make this task especially challenging. Herein, a strategy for taming radical redox reactions has been developed, in which solvent-bonding can alter the reactivity of the generated radical intermediates and thereby drastically alter  the reaction selectivity at room temperature. Various b-oxysulfoxides and b-hydroxy sulfides can be facilely obtained, some of which are difficult to synthesize by existing methods. Notably, neither a metal catalyst nor any further additives are necessary in these processes.

anie-WHM-2016

Angew. Chem. Int. Ed. 2016, 55, 1094 –1097

Link:http://onlinelibrary.wiley.com/doi/10.1002/anie.201508729/epdf

Welcome our new group member Prof. Dr. Chien-Wei Chiang

Welcome our new group member Prof. Dr.  Chien-Wei Chiang !!!

Chien-Wei Chiang

CV-江建伟Chien-Wei Chiang, Ph.D.
Associate Professor of Prof. Aiwen Lei’s Group
College of Chemistry and Molecular Sciences
Wuhan University
Luojiashan, Wuhan, China 430072

 

Education
National Taiwan Normal University, Taipei, Taiwan (2008-2012)
Ph.D. in Chemistry, November 2012
Advisor: Professor Way-Zen Lee
Thesis Title: C2-Symmetric Proline-Derivative Nickel Complexes for Mimicking the Functional Model
of Nickel Superoxide Dismutase and Their Application for thia-Michael Addition
National Taiwan Normal University, Taipei, Taiwan (2006-2008)
M.S. in Chemistry, June 2008
Advisor: Professor Way-Zen Lee
Thesis Title: Synthesis and Structure of Copper Complexes with a Polydentate Ligand Relevant to the
Active Site of Quercetin 2,3-dixoygenase
Fu-Jen Catholic University, New Taipei city, Taiwan (2002-2006)
B.S. in Chemistry, June 2006

Employment
2016 – Associate Professor, College of Chemistry and Molecular Science, Wuhan University, China
2015 –2016 Postdoctoral Fellow, Department of Chemistry, University of Cambridge, United Kingdom
2014 – 2015 Postdoctoral Fellow, Department of Chemistry, Academia Sinica, Taiwan
2013 Visiting Researcher, Department of Chemistry, University of Minnesota, United State
2013 – 2014 Postdoctoral Fellow, Department of Chemistry, National Taiwan Normal University, Taiwan

Publications
1. C.-W. Chiang, S.-R. Wen, G.-C. Lee, C.-H. Lin, T.-C. Kuo, C.-H. Lin, T.-S. Kuo, and W.-Z. Lee*
“Synthesis and Reactivity of a Functional Synthetic Mimic for Nickel Superoxide Dismutase” 2016,
Submitted.
2. C.-W. Chiang, S. T. Kleespies, C.-H. Lin,* E. L. Bominaar,* E. Münck,* L. Que, Jr.,* and W.-Z.
Lee* “Formation of an Iron(III)-Hydroperoxo Complex Directly from an Iron(III)-Superoxo
Intermediate” 2016, Submitted.
3. Heather D. Stout, Scott T. Kleespies, Chien-Wei Chiang, Way-Zen Lee, Lawrence Que, Jr., Eckard
Münck, and Emile L. Bominaar “Spectroscopic and Theoretical Study of Spin-dependent Electron
Transfer in an FeIII−Superoxo Complex” 2016,Submitted.
4. C.-W. Chiang, S. T. Kleespies, H. D. Stout, E. L. Bominaar,* L. Que, Jr.,* E. Münck,* and W.-Z.
Lee* “Characterization of a Paramagnetic Mononuclear Nonheme Iron-Superoxo Complex” J. Am.
Chem. Soc. 2014, 136, 10846−10849.
5. C.-W. Chiang, Y.-L. Chu, H.-L. Chen, T.-S. Kuo, and W.-Z. Lee* “Synthesis and Characterization
of NiIIIN3S2 Complexes as Active Site Models for the Oxidized Form of Nickel Superoxide
Dismutase” Chem. Eur. J. 2014, 6283-6286
6. B. Gopula, C.-W. Chiang, W.-Z. Lee, T.-S. Kuo, P.-Y. Wu, J. P. Henschke, and H.-Liang Wu*
“Highly Enantioselective Rh-Catalyzed Alkenylation of Imines: Synthesis of Chiral Allylic Amines
via Asymmetric Addition of Potassium Alkenyltrifluoroborates to N-Tosyl Imines” Org. Lett. 2014,
16, 632-635.
7. K.-C. Huang, B. Gopula, T.-S. Kuo, C.-W. Chiang, P.-Y. Wu, J. P. Henschke and H.-L. Wu* ”
Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to β-Nitroolefins: Formal Synthesis
of (S)-SKF 38393 ” Org. Lett. 2013, 15, 5730-5733.
8. W.-Z. Lee,* C.-W. Chiang, G. M. Kulkarni, and T.-S. Kuo “Highly Efficient Proline Ester-Based
Catalysts for Michael Addition of Thiophenols to α,β-Enones” J. Chin. Chem. Soc. 2013, 60,
245-250.
9. W.-Z. Lee,* C.-W. Chiang, T.-H. Lin, and T.-S. Kuo “A Discrete Five-Coordinate NiIII Complex
Resembling the Active Site of the Oxidized Form of Nickel Superoxide Dismutase” Chem. Eur. J.
2012, 18, 50-53.

Patent
1. W.-Z. Lee, C.-W. Chiang, T.-H. Lin, T.-S. Kuo, “Ni complex and its derivatives,
producing method, and the use thereof as an antioxidant”, US 2013/0317224 A1, CA 2788470
A1, CN 103421049A, DE 102012111306A1.
Awards
1. Student Award of 5th Asian Biological Inorganic Chemistry Conference, 2010
2. PhD Research Excellence Award, National Taiwan Normal University, 2012
3. Postdoctoral Research Abroad Fellowship (MOST), 2014

Teaching Activities
09/2008 – 06/2011: Teaching Assistant – Inorganic Chemistry Laboratory, National Taiwan
Normal University, Taiwan.
09/2008 – 01/2009: Teaching Assistant – Bioinorganic Chemistry, National Taiwan Normal
University, Taiwan.
Oral at Conference
“Mechanistic and Reactivity Studies of Organic Molecules Activation by Transition Metal Complexes”
Taiwan Scientific Symposium, (United Kingdom) – June 2015
Poster at Conferences
Asian Biological Inorganic Chemistry Conference, AsBIC (Korea) – November 2008
Asian Biological Inorganic Chemistry Conference, AsBIC (Taiwan) – November 2010
International Conference on Biological Inorganic Chemistry, ICBIC (Canada) – August 2011
Asian Biological Inorganic Chemistry Conference, AsBIC (Hong-Kong) – November 2012
International Conference on Biological Inorganic Chemistry, ICBIC (France) – July 2013
Asian Biological Inorganic Chemistry Conference, AsBIC (Australia) – November 2014